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The hypermobility syndrome(HMS) was very first described in 1967 by Kirk et al as the event of musculoskeletal symptoms in hypermobile healthy persons. On the other hand, other names are offered to HMS, such as joint hypermobility syndrome and benign hypermobility joint syndrome. HMS is a dominant inherited connective tissue condition described as "generalized articular hypermobility, with or without subluxation or dislocation.
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Hypermobility syndrome is various from localized joint hypermobility and other disorders that have actually generalized joint hypermobility, such as Ehlers-Danlos Syndrome, Rheumatoid Arthritis, Systemic Lupus Erythematosus, and Marfan Syndrome. Need More Info? may take place also in chromosomal and hereditary conditions such as Down syndrome and in metabolic disorders such as homocystinuria and hyperlysinemia.
Scientifically Relevant Anatomy [edit edit source] The pathophysiology in Hypermobility Syndrome is not yet totally understood, it seems a systemic collagen abnormality. The problem in collagen ratios is related with joint hypermobility and laxity of other tissues. The ratio of collagen (type I, II and III) is decreased in the skin.
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HMS also impacts the joint position sense. Joint hypermobility takes place usually in kids and lowers with age. Joint movement is highest at birth, there is a decrease in kids around 9 to twelve years old. In teen ladies, there is a peak at the age of fifteen years, after this age the joint movement decreases, as well in boys as in women.